The Yan lab studies one of the fundamental questions in microbiology: how bacteria adapt to the various environmental stresses in their ecological niches, animal host, as well as clinical settings and develop antimicrobial resistance. We aim to uncover the detailed signal transduction systems involved in these processes and translate the knowledge into anti-infective, anti-resistance interventions. We tackle these important and fundamental questions at the level of gene expression, coupled with cutting-edge interdisciplinary approaches such as multi-omics, CRISPR-Cas, genetic codon expansion, photo cross-linking etc..

 

A.Yan's lab group photo (2009Sept)
The Yan lab, 2019

We always welcome the bright minds to join us. Together, we pursue excellence in academics and your own dreams.