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B.Sc. (Shanxi),  Ph.D. (Peking)

Associate Professor
Molecular Microbiology and Biochemistry

Mailing address:
School of Biological Sciences
The University of Hong Kong
Pokfulam Road, Hong Kong

Tel: (852) 2299 0864
Fax: (852) 2559 9114
E-mail: ayan8@hku.hk
Office: 7S-01 Kadoorie Biological Sciences Building

Aixin Yan's image

 Fellowships:


 Awards and Honors (selected):

* Young Investigator’s Award, Hong Kong Society of Immunology, 2013.

* Best Oral Presentation Award, The Annual Scientific Meeting of the Hong Kong Society of Immunology, Hong Kong, May 25, 2013.

* Federation of European Microbiological Societies (FEMS) Young Scientist Meeting Grant, "7th European Workshop on Bacterial Respiratory Chains", Backagården, Höör, Lund, Sweden, 2011.

* HKU Overseas Fellowship Award, HKU, 2010.

* Poster-Presentation Award at the Kenneth B. Raper Symposium for Microbiology, University of Wisconsin-Madison, Madison, WI, USA, August 31, 2007.

* Traveling Award for the 11th EMBO-FEBS Advanced Lecture Course on "Molecular and Cellular Biology of Membranes", June 18-29, Corsica, France, 2007.

* Traveling Award for the US-Japan Glyco 2004, November 17-21, Honolulu, Hawaii, USA, 2004.

* Traveling Award for the IUBMB/ASBMB 2004 meeting, June 12-16, Boston, MA,USA, 2004.

*  Excellent graduate student, Peking University, Beijing, China, 2001.

* Excellent Young Scientist Award in the Peptide Field bestowed by the 6th Chinese International Peptide Symposium (CPS), July, Mount Huang, China, 2000.


 Teaching:

BIOL 2103 Biological Science Laboratory Course (Module II. Basic Microbiology Techniques)

BIOL 3508 Microbial Physiology and Biotechnology

BIOL 4401 Clinical Microbiology and Applied Immunology

BIOL 3993 Directed Studies in Molecular & Biotechnology

BIOL 4963 Molecular & Biotechnology Internship

BIOL 4993 Molecular & Biotechnology Project​

 

 Publications:

  1. "An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli"
    Yan, A.; Guan, Z., Raetz, C. R. H.  J. Biol. Chem. 2007, 282, 36077-36089.
  1. "Two Oligosaccharyl Transferase complexes exist in yeast and associate with two different translocons."
    Yan, A.
    ; Lennarz, W. J. Glycobiology 2005, 15, 1407-1415.
  1. "Studies of yeast oligosaccharyl transferase subunits using the split-ubiquitin system: topological features and in vivo interactions."
    Yan, A.; Wu, E.; Lennarz, W. J. Proc. Natl. Acad. Sci. U. S. A., 2005, 102, 7121-7126.
  1. "Interaction of the OT subunits with the translocon complex."
    Chavan, M.; Yan, A.; Lennarz, W. J. J. Biol. Chem. 2005, 280, 22917-22924.
  1. "Enzymatic synthesis and bioactivity of estradiol derivative conjugates with different amino acids."
    Yan, A;Chan, R. Y. K.; Lau, W. S.; Lee, K. S.;  Wong, M. S.; Xing, G. W.; Tian, G. L.; Ye, Y. H. Tetrahedron, 2005, 61, 5933-5941.
  1. "Unraveling the mechanism of protein N-glycosylation."
    Yan, A.; Lennarz, W. J.  J. Biol. Chem. 2005, 280, 3121-3124.
  1. "Evidence for the existence of two distinct Oligosaccharyl Transferase complexes in the yeast Saccharomyces cerevisiae."
    Yan, A.; Lennarz, W. J. Glycobiology, 2004, 14, 1116.
  1. "Probing the Peptide Substrate Binding Site of Oligosaccharide Transferase by Using Competitive Inhibitors."
    Yan, A.; Lennarz, W. J, FASEB J., 2004, 18, C176.
  1. "New findings on the interactions among the Yeast Oligosaccharyl Transferase Subunits Using a Chemical Cross-linker."
    Yan, A.; Eilaf, A.; Yan, Q.; Lennarz, W. J.  J. Biol. Chem. 2003, 278, 33078-87.
  1. "Interaction between OT subunit Wbp1p and yeast protein kinase C: insight into the functional relationship."
    Yan, A.; Wu, E.; Lennarz, W. J. Glycobiology, 2003, 13, 858.
  1. "Effects of Properties of Organic Solvents and Water Content on the Enzymatic synthesis of Derivatives of Dipeptides Containing D-Amino Acid Residues."
    Shen, H.Y., Tian, G. L.; Yan, A.; Jia, Y.; Hong, Y. Y.; Ye, Y. H.  Acta Chim. Sini., 2003, 61, 1144-1148. (CAN 140: 128667)
  1. "Interaction of Oligosaccharide Transferase subunits in the yeast Saccharomyces cerevisiae."
    Yan, A.; Lennarz, W. J., Mol. Biol. Cell2002, 13, 233a
  1. "Recent progress on the immobilization of enzymes on molecular sieves for the reactions in organic solvent."
    Yan, A.;  Li, X. W.; Ye, Y. H. Appl. Biochem. Biotechnol. 2002, 101, 113-129.
  1. "New developments on protease-catalyzed organic synthesis."
    Yan, A.; Tian, G. L.; Ye, Y. H. Chinese Journal of Chemistry Progress, 2001, 13, 203-208. (in Chinese, CAN 136: 231901)
  1. "Isolation and identification of 2-(1', 2', 3', 4'-tetrahydroxybutyl)-6-(2", 3", 4"-trihydroxybutyl)-pyrazine from Panax pseudoginseng var notoginseng."
    Li, Q.; Yan, A.; Ye, Y. H.; Xing, Q. Y. Acta Scientiarum Naturalium Universitatis Pekinensis.", 2001, 37, 286-288. (CAN 137: 90951)
  1. "Synthesis of N-protected amino acid-estradiol derivatives catalyzed by subtilisin in organic solvent."
    Yan, A.; Xing, G. W.; Ye, Y. H. et al., Peptide: Biology and Chemistry (Proceedings of the 6th Chinese Peptide Symposium), Eds: Jie-cheng Xu, Hong-yan Xu, Jams P. Tam, Science Press, Shanghai, China, 2001.
  1. "Isolation, identification and physiological activities of 2-(1', 2', 3', 4'-tetrahydroxybutyl)-6-(2", 3", 4"-trihydroxybutyl)-pyrazine from Panax notoginseng."
    Li, Q.; Ye, Y. H.; Zhou, Y. W.; Shen, H.; Xing, Q. Y. Chemical Journal of Chinese Universities, 2001, 22, 1824-1828. (in Chinese, CAN 136: 131557)
  1. "Synthesis of N-protected amino acid trifluoroethyl esters by the catalysis of 4-dimethylaminopyridine (DMAP)."
    Liu, P.; Yan, A.; Ye, Y. H. Chinese Journal of Hua Xue Tong Bao, 2001, No. 12, 777-780. (in Chinese CAN: 136:340953).
  1. "Progress in modification of peptides with non-protein amino acids and their application inn the structure-activity relationship."
    Yan, A.; Tian, G. L.; Ye, Y. H. Chinese Journal of Organic Chemistry, 2000, 20, 299-305. (in Chinese, CAN 133:68261)
  1. "Study on the enzymatic synthesis of N-protected amino acid-estradiol derivatives in organic solvent."
    Yan, A.; Xing, G. W.; Ye, Y. H.; Tian, G. L.; Wong, M. S.; Lee, K. S.; Tetrahedron Lett. 2000, 41, 5379-5381.